Unmet clinical need

•67-year old male patient
•No previous medical history
•Presents in the Emergency Department with:

  1. Acute kidney injury (Creatinine=2.6 mg/dl)

  2. Thrombocytopenia (PLTs: 30x103/μl)

  3. Non-immune hemolytic anemia

  - Hb: 7.8 g/dl

  - LDH: 475 mg/dl

  - DAT negative

Which test would you order first to establish the patient’s diagnosis?

  • ADAMTS13 activity
  • Peripheral blood smear for schistocytes
  • Renal ultrasound
  • Bone Marrow Aspirate

Map: TMA (792)
Node: 16184
Score:

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OpenLabyrinth
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  • La actividad es la pintura.
  • A atividade é cozinhar.
  • Opțiunea 1: A și C sunt corecte
  • new node
  • Terbutaline
  • Glyceryl trinitrate (organic nitrate)
  • Watch and wait until further testing is available
  • geiaa
  • Ζωγραφική.
  • Secuenciación del genoma
  • ΙΣΤΟΡΙΚΟ
  • >Ο θόρυβος της εικόνας θα μειωθεί κατά 40%
  • Root Node
  • Refuse to take drugs, because I already feel better.
  • >Ο θόρυβος της εικόνας θα αυξηθεί
  • Λήψη ιατρικού ιστορικού.
  • Start complement inhibition (eculizumab/ravulizumab)
  • new node
  • Switch to audio + chat mode and promise a PDF summary afterward
  • Labour
  • Unmet clinical need

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