Excellent! Propylthiouracil works by inhibiting thyroid peroxidase-catalyzed reactions. It has also been implicated in inhibition of de-iodination of T4. 

Over the next month, Sam regularly forgets to take her medication. She puts that down to 'pregnancy brain' and is not too concerned about it.  

Later that evening, Sam starts to feel very unwell. She is sweating profusely, has a fever and her heart is racing. Her husband takes her to the Emergency Department, where thyroid storm is diagnosed. 

What is the most appropriate management for Sam? 

STOP AND DISCUSS