Dapagliflozin

Excellent! Dapagliflozin is an SGLT2 inhibitor that blocks SGLT2 in the proximal tubule, leading to increased urinary glucose excretion and mild osmotic natriuresis. This produces modest weight loss and blood pressure reduction, lowers preload, and reduces intraglomerular pressure, which contributes to kidney protection. Clinically, it reduces heart failure hospitalizations and cardiovascular death in HFrEF irrespective of diabetes status, and provides modest glucose lowering in type 2 diabetes.

The cardiologist explains that caution is needed with this drug because Mr. Green will also be taking a diuretic and therefore they will need to monitor very closely.

Endocrinology Follow-Up

The endocrinologist informs Mr. Green that his HbA1c is within the target range. He has also managed to lose 5kg. You are surprised that Mr. Green is not happier with these results as he is clearly pre-occupied with his own thoughts.

You ask him whether everything else is going well. He nods his head initially and then tells you that Rachel, his 29-year old daughter, who is about 5-months pregnant, has just been diagnosed with gestational diabetes. Mr. Green blames himself as he knows that diabetes can be passed onto your children. Dr. McPhee reassures Mr. Green that this is a common condition and many women manage it well, with no complications for the patients or the baby. He asks Mr. Green whether his daughter is taking insulin. Mr. Green replies that his daughter hates needles and is reluctant to take any shots.

Therefore her doctor recommended another drug, which she can take as a tablet.

Which drug was most likely prescribed?

  • Pe halat se pot transfera materiale periculoase în exteriorul laboratorului și se poate contamina zona [undo]
  • 50nm to 1mm [undo]
  • Doesn't listen to her friends and keeps drinking [undo]
  • Answer 3 [undo]
  • Coffee helps a bit with her daily activities but disrupts her sleep [undo]
  • Răspunsul 1 [undo]
  • Admission [undo]
  • Лікування веде до поліпшення. [undo]
  • Use Punnett squares and the multiplication rule. [undo]
  • Traits [undo]
  • De la 1 cm până la 10 m [undo]
  • Option 3 [undo]
  • Thank you for telling me—this is a lot to carry, and it’s okay to cry. [undo]
  • Επιλογή 3 [undo]
  • Opción 2 [undo]
  • Option 2 [undo]
  • Motor Exam [undo]
  • Allele [undo]
  • Prophase, prometaphase, metaphase, anaphase, telophase [undo]
  • A microscope that uses light source to magnify objects [undo]
  • Epilogue [undo]
  • Εργαστηριακοί Ζυγοί I [undo]
  • Option 1 [undo]
  • Profază, prometafază, metafază, anafază, telofază [undo]
  • EcoRI [undo]
  • Nebulized ipratropium [undo]
  • The result [undo]
  • Opción 1 [undo]
  • His mother is going to be fine. [undo]
  • It’s okay to feel this way [undo]
  • Restriction Endonuclease Digestion: Optimal Conditions [undo]
  • Metformin [undo]
  • Laboratory Scales II [undo]
  • Conuri de pin [undo]
  • Gynaecomastia [undo]
  • Πέψη DNA με Περιοριστικές Ενδονουκλεάσες : Βέλτιστες Συνθήκες [undo]
  • Exenatide [undo]
  • Propose LLMc to Andreas [undo]
  • 37 °C, niveles atmosféricos de O₂, niveles atmosféricos de CO₂ [undo]
  • Interphase, prophase, metaphase, anaphase, telophase [undo]
  • Selective permeability [undo]
  • The end [undo]
  • Dapagliflozin [undo]

Map: Michael Green_GEMD_1 (1115)
Node: 21102
Score:

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