Cochrane Database Systematic Review

Your computer screen displays an abstract from the Cochrane Database of Systematic Reviews. Several key sentences are highlighted in yellow:

• 'Selection Criteria: Randomized controlled trials comparing glucosamine with placebo.'

• 'Main Results: 25 studies included. Glucosamine failed to show a clinically significant benefit for pain reduction compared to placebo (Standardized Mean Difference -0.17).'

• 'Safety: No significant difference in adverse events between glucosamine and placebo.'

You quickly read the Systematic Review abstract. Based on the highlighted data above, which is the most accurate conclusion you would hold before speaking with the patient again?