Mechanism of action of PPIs

In considering the mechanism of action of PPIs, which statement best explains their therapeutic effect in Mr. Mason? 

  • PPIs are weak acids activated by protonation in parietal cells
  • PPIs are weak bases activated by protonation in parietal cells
  • PPIs are weak bases that become activated by colonic bacteria
  • PPIs are weak bases converted by CYP450 enzymes to the active form in parietal cells
  • PPIs are weak acids converted by CYP450 enzymes to the active form in parietal cells

Map: Connor Mason_UNIC (1100)
Node: 20904
Score:

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  • Amlodipine (calcium channel blocker)
  • Option 1
  • Overstaining of the cells
  • Glyceryl trinitrate (organic nitrate)
  • The patient’s urine contains glucose.
  • Calcium: Increased; Potassium: Decreased; Sodium: Increased
  • Calcium: Decreased; Potassium: Decreased; Sodium: Decreased
  • Όλες οι περιοχές που εξετάστηκαν είναι επιμολυσμένες.
  • new node
  • Identification test for protein.
  • new node
  • Verapamil (calcium channel blocker)
  • Fibrosis quística: Planteamiento del caso
  • De 5nm a 100μm
  • Mechanism of action of PPIs

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