Decreased levels of HDL

Are you sure? This would not be beneficial, remember that increased HDL may be beneficial and statins in fact can raise, not decrease HDL levels. Statins primarily reduce LDL and modestly reduce triglycerides. HDL usually rises slightly or is unchanged.  

Please go back and re‑consider.  

Grapefruit-simvastatin (statin) interaction

Map: Mattias Garcia_ORU (1096)
Node: 20728
Score:

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OpenLabyrinth
OpenLabyrinth is an open source educational pathway system

Review your pathway

  • Glyceryl trinitrate (organic nitrate)
  • Furosemide
  • Digoxin (digitalis, positive inotropic drug)
  • Increased elimination of cholesterol
  • Sacubitril-valsartan (ARNI)
  • Ramipril (ACE inhibitor)
  • Glyceryl trinitrate (organic nitrate)
  • Decreased levels of HDL
  • Decreased absorption of dietary cholesterol
  • Decreased absorption of dietary cholesterol
  • Increased LDL uptake in hepatocytes
  • Warfarin may be commenced as an alternative to apixaban
  • Increased elimination of cholesterol
  • Decreased levels of HDL

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