Increased elimination of cholesterol

Dr. Kyriacou explains that this is a good answer as it would reduce LDL levels, but this is not the accepted mechanism for statins. Bile acid sequestrants increase faecal elimination of bile acids; that is a different class of drugs.  

Please go back and re‑consider. 

Grapefruit-simvastatin (statin) interaction

Map: Mattias Garcia_ORU (1096)
Node: 20726
Score:

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OpenLabyrinth
OpenLabyrinth is an open source educational pathway system

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  • Glyceryl trinitrate (organic nitrate)
  • Furosemide
  • Digoxin (digitalis, positive inotropic drug)
  • Increased elimination of cholesterol
  • Sacubitril-valsartan (ARNI)
  • Ramipril (ACE inhibitor)
  • Glyceryl trinitrate (organic nitrate)
  • Decreased levels of HDL
  • Decreased absorption of dietary cholesterol
  • Decreased absorption of dietary cholesterol
  • Increased LDL uptake in hepatocytes
  • Warfarin may be commenced as an alternative to apixaban
  • Increased elimination of cholesterol

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