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•Starts plasma exchange (x3) and steroids
•LDH decrease, but platelets and creatinine remain abnormal
•Shiga toxin: negative
•No evident underlying causes – normal B12
•ADAMTS13: 45%
What do we do next?


Start caplacizumab and rituximab, without plasma exchange
Start complement inhibition (eculizumab/ravulizumab)

Map: TMA (792)
Node: 16362
Score:

reset

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