Mr. Hartono and his wife leave feeling burdened and intimidated

Mr. Hartono and his wife leave feeling burdened and intimidated. Once home, the 10-page manual is quickly abandoned. Because the barrier to entry for the daily check-in remains too high, the required daily adherence monitoring (DOTs) fails. If Mr. Hartono experiences minor side effects in the coming days, he is highly unlikely to report them, increasing the risk of treatment interruption.