Grapefruit-aspirin interaction

Dr. Kyriacou explains that it is unlikely that Mr. Garcia’s presentation is due to a grapefruit-aspirin interaction. Grapefruit does not have a clinically important interaction with low‑dose aspirin. Even if grapefruit juice, a CYP450 inhibitor, interacted with aspirin, salicylate toxicity presents with tinnitus, hyperventilation, and acid–base disturbance, not profound myopathy with very high creatine kinase. 

Please go back and re‑consider. 

Presentation

Map: Mattias Garcia_UNIC (1092)
Node: 20633
Score:

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  • Emergency Department
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  • Grapefruit-aspirin interaction

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