Adverse effect due to heparin

Well-done! Heparins have been associated with heparin-induced thrombocytopenia (HIT), an immune-mediated reaction that manifests early in the treatment with heparins. Even though HMWH is more likely to cause HIT, LMWH can also cause it in some patients.

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You decide to discontinue heparin as five days have elapsed and the INR indicates that warfarin has reached its maximal pharmacological effects. 

Further Developments

Two months later, Kylie is back to her old self, settling back into her routine, when she develops an upper respiratory tract infection, with a sore throat. Her general practitioner prescribes erythromycin (macrolide antibiotic). Kylie is also taking an over-the-counter remedy, which includes a decongestant and aspirin.

A few days later, she visits her doctor because, even though her cold is improving, she notices that her stools are loose, black and smelly. She also notices bruises on her skin. Her INR is found to be 7.0. Your supervisor asks you what you think may have happened. 

What is the most appropriate treatment for Kylie?